Saudi Arabian Foreign Minister Adel al-Jubeir joined Israeli Prime Minister Benjamin Netanyahu in blaming Iran for rising regional tensions, at the Munich Security Conference on Sunday.
Jubeir called for "fundamental change in the Iranian regime" and accused it of trying to impose an "empire" across the Middle East.
He noted "problems in the Middle East began" with the Iranian revolution of 1979, which he said "unleashed sectarianism" in the region.
The events of 1979 led to the establishment of Hezbollah, which is "the world's most dangerous terrorist organisation", Jubeir said. He then condemned Iran for arming the Houthis, a claim Tehran has previously denied.
"We didn't attack Iran. Iran is the one that is attacking us. Iran has started to undermine Lebanon, Syria, Iraq, Bahrain, Yemen, Pakistan, Afghanistan, including countries in Africa," Al Jazeera cited the minister as saying.