Nine people were killed as a result of the blast in Syria's Manbij, Al Jazeera reported on Twitter.
According to the local military council, the blast occurred near a patrol of the international coalition in the city.
"Nine civilians were killed and 20 others wounded as a result of an explosion in the centre of the city of Manbij, while a US military patrol was passing," the broadcaster reported.
ISIS terrorist group has reportedly claimed responsibility for the attack.