UK Defence Secretary Michael Fallon has announced that HMS Daring will soon be supporting the military campaign against Daesh militants in Iraq and Syria.
HMS Daring, which has a crew of 190, will sail from Portsmouth to the Gulf on Friday.
The warship will help protect US aircraft carriers engaged in bombing raids against Daesh targets and provide information to the headquarters controlling air operations.
As part of the deployment, the Type 45 destroyer will be patrolling some of the world's busiest shipping lanes.
Mr Fallon said: "All three armed services are making a vital contribution to defeating Daesh. RAF aircraft are hitting the terrorists daily on the ground; the Army is providing counter-explosives training to Iraq troops; the Royal Navy helps protect coalition carriers in the Gulf as they launch strikes. With the biggest defence budget in Europe and the second biggest in Nato, our Armed Forces are making a real difference around the world".