The Soyuz MS-03 spacecraft with three crew members blasted off from the Baikonur space center in Kazakhstan late Thursday and reached orbit several minutes later, a Roscosmos spokesman said.
"The spacecraft separated from the third stage of the Soyuz-FG rocket," TASS cited him as saying.
The spacecraft carries Russian cosmonaut Oleg Novitskiy, European Space Agency astronaut Thomas Pesquet and NASA astronaut Peggy Whitson.
It is the 50th mission to the ISS.